21.07.10 - Baclofen-induced chorea in CRPS-related dystonia

Baclofen is often used in the treatment of primary and secondary dystonia on CRPS patients. To overcome baclofen’s poor ability to pass the blood-brain barrier, intrathecal administration of baclofen (ITB) can be used.
Van der Plas, Van Rijn & Van Hilten (2010) described four patients while on the baclofen treatment, of which three on continuous ITB. The findings suggest that there is an increased susceptibility of chorea (an abnormal involuntary movement disorder) on CRPS patients who were administered by baclofen.

Title: Baclofen-induced chorea in complex regional pain syndrome-related dystonia
Authors: A.A. van der Plas, M.A. van Rijn, and J.J. van Hilten
In: Movement Disorders
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